I know that books I have written will still resonate in 50 years - particularly 'My Sister's Keeper.' It has sold three million copies in the States alone. I strongly feel that as a novelist you have a platform and the ability to change people's minds.
A globalized world is by now a familiar fact of life. Building walls or moats may sound appealing but the future belongs to those who tend to their people and then boldly engage the rest of the world near and far.