I've been advised not to have any more children for medical reasons so that's it - the shop has closed even though I would have loved a daughter.
I know for works for me - those wonderful sad love songs.
Sometime they don't let you know that they know that they don't know...
I'm really convinced that our descendants a century or two from now will look back at us with the same pity that we have toward the people in the field of science two centuries ago.