When you talk about obesity there's so many things that can cause that. It can be a medical thing or down to the individual. There's a lot of other things involved than eating a Mars bar.
You can never turn the clock back and since we're talking about mental...
Sometime they don't let you know that they know that they don't know...
Change is the principal feature of our age and literature should explore how people deal with it. The best science fiction does that head-on.