If your goal is anything but profitability - if it's to be big or to grow fast or to become a technology leader - you'll hit problems.
The underlying principles of strategy are enduring regardless of technology...
If we had had the right technology back then you would have seen Eva Braun...
We have not given science too big a place in our education but we have made a perilous mistake in giving it too great a preponderance in method in every other branch of study.