I admired Eugene McCarthy's courage and although I left his Senate staff after four years to accept a job as the researcher on the editorial page of the 'Washington Post ' I remained an admirer.

When I was 24 I was full of life. I was that ham who wanted to be famous a movie star all that stuff. I think it's cool. But it was not what I was searching for really. It was more a delusion.

You have riches and freedom here but I feel no sense of faith or direction. You have so many computers why don't you use them in the search for love?

The first legislation that I produced relating to the Internet was a bill to overturn a restriction inside of the law that prohibited the Internet backbone from being used for anything other than research and scientific and educational communication.

I started on the use of the Internet for scientific communication. Our research group was one of the very first to make really systematic use of it as a way of managing research projects.

I thought my life was mapped out. Research living in the forest teaching and writing. But in '86 I went to a conference and realised the chimpanzees were disappearing. I had worldwide recognition and a gift of communication. I had to use them.

I get heartfelt thanks from all kinds of people. Today I heard from a waitress in Georgia who has lost her job and is trying to figure out how her local bank can change the terms on her credit card and I heard from a physicist at a major research university who wants to explain a better theory of financial stress tests.

In Britain like most of the developed world stem-cell research is regarded as a great opportunity. America will be left behind if it doesn't change policy.

I read and walked for miles at night along the beach writing bad blank verse and searching endlessly for someone wonderful who would step out of the darkness and change my life. It never crossed my mind that that person could be me.

I want a car that will last 10 years or longer because I totally hate the process of researching shopping for a new car and then haggling for the price. I wish I could just snap my fingers and my car is there.

Every time I copy something I can draw it for the rest of my life. But research is so painful - I mean just opening up a magazine looking for a picture of a car or looking out the window looking for a car is just hard!

When they searched my car they said that they found a gasoline canister and I think duct tape. Who wouldn't have a gasoline canister on them when driving 3 000 miles across country?

I remember when metal was something you really had to search out and now I hear it on car commercials.

When I climb into my car I enter my destination into a GPS device whose spatial memory supplants my own. I have photographs to store the images I want to remember books to store knowledge and now thanks to Google I rarely have to remember anything more than the right set of search terms to access humankind's collective memory.

The Internet creates as well as destroys. Social networks search advertising and cloud computing are multibillion dollar industries that didn't exist 10 years ago. They are products of the same force that has rendered the Postal Service's core business obsolete.

Our combination of great research universities a pro-risk business culture deep pools of innovation-seeking equity capital and reliable business and contract law is unprecedented and unparalleled in the world.

There are pros and cons of experience. A con is that you can't look at the business with a fresh pair of eyes and as objectively as if you were a new CEO. Fire yourself on a Friday night and come in on Monday morning as if a search firm put you there as a turn-around leader. Can you be objective and make the bold change?

The entrepreneur always searches for change responds to it and exploits it as an opportunity.

As I approach my 88th birthday it's become apparent to me that my eyes and ears among other appurtenances aren't quite what they used to be. The prospect of long flights to wherever in search of whatever are not quite as appealing.

Research has shown that the best way to be happy is to make each day happy.

We think the Mac will sell zillions but we didn't build the Mac for anybody else. We built it for ourselves. We were the group of people who were going to judge whether it was great or not. We weren't going to go out and do market research. We just wanted to build the best thing we could build.

Search for beauty without features something deeper than any signs.

It is important to fund young researchers who want to do curiosity-driven research. Curiosity-driven research is a part of life. Some people are curious. They want to learn more about nature and society should help that. It's like art: you can learn more and bring more beauty.

I think we have become obsessed with beauty and personally I'm really saddened by the way women mutilate their faces today in search of that.