I have an almost complete disregard of precedent and a faith in the possibility of something better. It irritates me to be told how things have always been done. I defy the tyranny of precedent. I go for anything new that might improve the past.

Pharmaceutical companies are enjoying unprecedented profits and access with this Administration. Yet the Republicans' prescription drug plan for seniors has been a colossal failure and over 43 million Americans wake up every morning without health insurance.

We have actually experienced in recent months a dramatic demonstration of an unprecedented intelligence failure perhaps the most significant intelligence failure in the history of the United States.

If there's any object in human experience that's a precedent for what a computer should be like it's a musical instrument: a device where you can explore a huge range of possibilities through an interface that connects your mind and your body allowing you to be emotionally authentic and expressive.

So what we're talking about here is human rights. The right to live like a human. The right to live period. And what we're facing in Africa is an unprecedented threat to human dignity and equality.

Through all aspects of society be it art design the financial markets government technology or communications we are witnessing unprecedented global transformation - the result of which is impossible to predict.

We're living in an era of unprecedented change and I want to be a part of documenting it.

As human beings we are vulnerable to confusing the unprecedented with the improbable. In our everyday experience if something has never happened before we are generally safe in assuming it is not going to happen in the future but the exceptions can kill you and climate change is one of those exceptions.

Our combination of great research universities a pro-risk business culture deep pools of innovation-seeking equity capital and reliable business and contract law is unprecedented and unparalleled in the world.

Google is in an amazing position to be the target of tons of lawsuits that will set precedent for many important things for us on the Internet.