Never Have Your Dog Stuffed is really advice to myself a reminder to myself not to avoid change or uncertainty but to go with it to surf into change.

Investors have few spare tires left. Think of the image of a car on a bumpy road to an uncertain destination that has already used up its spare tire. The cash reserves of people have been eaten up by the recent market volatility.

We have some worse scenarios for which we need to prepare as companies. For the moment we're planning for the worst and the worst is now and the car market is down more than 15 percent in France. There is so much uncertainty.

Without the element of uncertainty the bringing off of even the greatest business triumph would be dull routine and eminently unsatisfying.

Medicine is a science of uncertainty and an art of probability.